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RMND1 Antibody, FITC conjugated

Datasheet
Code CSB-PA882123LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RMND1 Polyclonal antibody
Uniprot No.
Q9NWS8
Target Names
RMND1
Alternative Names
bA351K16 antibody; bA351K16.3 antibody; C6orf96 antibody; chromosome 6 open reading frame 96 antibody; FLJ20627 antibody; MGC117362 antibody; MGC149570 antibody; MGC882602 antibody; required for meiotic nuclear division 1 homolog (S. cerevisiae) antibody; Required for meiotic nuclear division protein 1 homolog antibody; Rmnd1 antibody; RMND1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Required for meiotic nuclear division protein 1 homolog protein (35-160AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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RMND1 Antibodies

RMND1 Proteins

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Target Background

Function
Required for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome.
Gene References into Functions
  1. Hearing impairment and renal failure are associated with RMND1 mutations. PMID: 26395190
  2. Expression of ESR1, RMND1 and CCDC170 associated with variants in separate enhancer elements predisposing breast cancer. [meta-analysis] PMID: 26928228
  3. Results demonstrate that the RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome. PMID: 23022098
  4. The RMND1 mutation caused haploinsufficiency that was rescued by overexpression of the wild-type transcript in mutant fibroblasts; this overexpression increased the levels and activities of mitochondrial respiratory-chain proteins. PMID: 23022099
Involvement in disease
Combined oxidative phosphorylation deficiency 11 (COXPD11)
Subcellular Location
Mitochondrion.
Protein Families
RMD1/sif2 family
Database Links

HGNC: 21176

OMIM: 614917

KEGG: hsa:55005

STRING: 9606.ENSP00000356272

UniGene: Hs.486835

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